Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrantoin SCHEMBL29582305 | 0.71 | TSHR (0.54) | ATMALDH1A1LMNASMN1; SMN2MAPT | |
| Tetrantoin SCHEMBL79518 | 0.71 | TSHR (0.54) | ATMALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL12405032 | 0.71 | TRIM24 (0.32) | ALDH1A1 | |
| SCHEMBL8640635 | 0.70 | OR51E2 (0.33) | LMNA | |
| SCHEMBL7824947 | 0.70 | SIGMAR1 (0.44) | ALDH1A1LMNAMAPTHTR2CPOLB | |
| SCHEMBL23855524 | 0.69 | TSHR (0.44) | HTR2CTSHRTDP1 | |
| SCHEMBL28442386 | 0.69 | TSHR (0.44) | HTR2CTSHRTDP1 | |
| SCHEMBL29386234 | 0.69 | TSHR (0.44) | HTR2CTSHRTDP1 | |
| SCHEMBL8378418 | 0.69 | ADRA2A (0.51) | ALDH1A1LMNAMAPTADRA2AHTR2C | |
| SCHEMBL8640104 | 0.69 | LMNA (0.33) | ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712845-B1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5633248-A | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS, DIARYLALKYLIDENEDIAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0712845-A1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |