Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829424 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4EL3MBTL1TP53MAPT | |
| SCHEMBL1720334 | 0.89 | CA2 (0.54) | ALDH1A1KDM4EL3MBTL1TP53MAPT | |
| SCHEMBL7814591 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1TP53MAPT | |
| SCHEMBL7814593 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1TP53MAPT | |
| SCHEMBL7827463 | 0.84 | CA2 (0.62) | ALDH1A1KDM4EL3MBTL1TP53MAPT | |
| SCHEMBL7827465 | 0.84 | CA2 (0.62) | ALDH1A1KDM4EL3MBTL1TP53MAPT | |
| SCHEMBL7823200 | 0.82 | CA2 (0.49) | ALDH1A1SMN1; SMN2PTGS2PTGS1CA2 | |
| SCHEMBL7823202 | 0.82 | CA2 (0.49) | ALDH1A1SMN1; SMN2PTGS2PTGS1CA2 | |
| SCHEMBL24849465 | 0.81 | KMT2A (0.61) | ALDH1A1KDM4ETP53MAPTSMN1; SMN2 | |
| SCHEMBL15941169 | 0.81 | KMT2A (0.61) | ALDH1A1KDM4ETP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |