Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828050 | 0.82 | RAB9A (0.61) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL7828043 | 0.82 | RAB9A (0.61) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL8353423 | 0.74 | LMNA (1.00) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL18906020 | 0.74 | RAB9A (0.79) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL23011774 | 0.74 | ALDH1A1 (0.84) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL3647261 | 0.73 | MAPK1 (0.76) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL6816533 | 0.72 | SMN1; SMN2 (0.84) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL8353836 | 0.70 | LMNA (0.67) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL29106508 | 0.70 | MEN1 (0.76) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL30701883 | 0.70 | MEN1 (0.76) | SMN1; SMN2HTTRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |