Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828043 | 1.00 | RAB9A (0.61) | RAB9ABLMKCNK3KCNK9LMNA | |
| SCHEMBL18906020 | 0.87 | RAB9A (0.79) | RAB9ABLMKCNK3KCNK9LMNA | |
| SCHEMBL7828047 | 0.82 | SMN1; SMN2 (0.64) | RAB9ABLMKCNK3KCNK9LMNA | |
| SCHEMBL6816359 | 0.79 | ALDH1A1 (0.67) | RAB9ABLMKCNK3KCNK9LMNA | |
| SCHEMBL8353423 | 0.76 | LMNA (1.00) | RAB9ABLMKCNK3KCNK9LMNA | |
| SCHEMBL29029973 | 0.76 | RAB9A (0.68) | RAB9ABLMKCNK3KCNK9LMNA | |
| SCHEMBL23011774 | 0.75 | ALDH1A1 (0.84) | RAB9ABLMKCNK3KCNK9LMNA | |
| SCHEMBL3647261 | 0.75 | MAPK1 (0.76) | RAB9ABLMKCNK3KCNK9LMNA | |
| SCHEMBL16179719 | 0.74 | ALDH1A1 (0.70) | RAB9ABLMKCNK3KCNK9LMNA | |
| SCHEMBL7948473 | 0.73 | RAB9A (0.59) | RAB9ABLMKCNK3KCNK9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |