Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP9 | P55211 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2499216 | 0.79 | CYP1A2 (0.50) | CYP2A6CYP1A2ALDH1A1MAPTCASP3 | |
| SCHEMBL18789067 | 0.76 | ALDH1A1 (0.48) | CYP2A6CYP1A2ALDH1A1MAPTCA1 | |
| SCHEMBL10897643 | 0.76 | CYP1A2 (0.52) | CYP2A6CYP1A2ALDH1A1MAPTCASP3 | |
| SCHEMBL97418 | 0.72 | CYP1A2 (0.52) | CYP2A6CYP1A2ALDH1A1MAPTCA1 | |
| SCHEMBL7839257 | 0.72 | GPR84 (0.45) | ALDH1A1MAPTL3MBTL1HSD17B10KDM4E | |
| SCHEMBL7841910 | 0.72 | CA1 (0.46) | CYP2A6CYP1A2ALDH1A1MAPTCA1 | |
| SCHEMBL8129822 | 0.71 | L3MBTL1 (0.42) | CYP2A6CYP1A2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL20398651 | 0.71 | GPR84 (0.46) | CYP2A6CYP1A2ALDH1A1MAPTCA1 | |
| SCHEMBL183369 | 0.71 | GPR84 (0.48) | CYP2A6CYP1A2ALDH1A1CA1CA2 | |
| SCHEMBL20398625 | 0.70 | ALDH1A1 (0.50) | CYP2A6CYP1A2ALDH1A1MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |