Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | RORC | P51449 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119616 | 0.90 | L3MBTL1 (0.72) | L3MBTL1RORCMEN1KMT2AKEAP1 | |
| SCHEMBL1631811 | 0.85 | KEAP1 (0.66) | L3MBTL1RORCKEAP1NFE2L2MAPT | |
| SCHEMBL7821545 | 0.85 | L3MBTL1 (0.53) | L3MBTL1RORCMEN1KMT2AKEAP1 | |
| SCHEMBL24279586 | 0.81 | MEN1 (0.60) | L3MBTL1RORCMEN1KMT2AHPGD | |
| SCHEMBL1630305 | 0.79 | KEAP1 (0.71) | L3MBTL1MEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL24279539 | 0.78 | RORC (0.70) | RORCHPGDHTTMAPT | |
| SCHEMBL121206 | 0.77 | RORC (0.70) | RORCHPGDHTTMAPT | |
| SCHEMBL7813073 | 0.77 | KEAP1 (0.68) | MEN1KMT2AKEAP1NFE2L2HTT | |
| SCHEMBL120825 | 0.76 | HPGD (0.61) | L3MBTL1RORCMEN1KMT2AHPGD | |
| SCHEMBL27849029 | 0.76 | HPGD (0.72) | L3MBTL1RORCMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |