SCHEMBL7828296

SCHEMBL7828296

O=C(O)CCOc1ccc(SF)cc1

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.61
MMP2 P08253 1/20 0.53
TSHR P16473 1/20 0.46
FFAR1 O14842 3/20 0.46
LMNA P02545 1/20 0.46
PPARA Q07869 2/20 0.45
MAPT P10636 1/20 0.45
LTA4H P09960 3/20 0.44
PLA2G4B P0C869 2/20 0.44
MCL1 Q07820 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3940213 0.90 PPARA (0.58) L3MBTL1FFAR1PPARAPLA2G4B
SCHEMBL10637841 0.82 L3MBTL1 (0.66) L3MBTL1MMP2TSHRFFAR1LMNA
SCHEMBL11333923 0.82 L3MBTL1 (0.61) L3MBTL1MMP2TSHRFFAR1LMNA
SCHEMBL6234737 0.82 L3MBTL1 (0.61) L3MBTL1MMP2TSHRFFAR1LMNA
SCHEMBL652824 0.79 L3MBTL1 (0.67) L3MBTL1MMP2TSHRFFAR1LMNA
SCHEMBL1822418 0.79 L3MBTL1 (0.67) L3MBTL1MMP2TSHRFFAR1LMNA
SCHEMBL3947736 0.78 MMP12 (0.44) L3MBTL1MMP2PPARAPLA2G4B
SCHEMBL2468006 0.77 L3MBTL1 (0.69) L3MBTL1MMP2TSHRFFAR1LMNA
SCHEMBL38674 0.77 L3MBTL1 (0.68) L3MBTL1MMP2TSHRFFAR1LMNA
SCHEMBL11682151 0.76 L3MBTL1 (0.67) L3MBTL1MMP2TSHRFFAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed