SCHEMBL3947736

SCHEMBL3947736

O=C(O)CC(O)CCOc1ccc(SF)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
POLB P06746 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MMP13 P45452 4/20 0.42
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.39
ALOX5 P09917 3/20 0.39
PPARG P37231 3/20 0.39
PPARA Q07869 3/20 0.39
PTGES O14684 2/20 0.38
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
MMP9 P14780 2/20 0.37
S1PR1 P21453 1/20 0.37
S1PR3 Q99500 1/20 0.37
MMP2 P08253 1/20 0.37
MMP14 P50281 1/20 0.37
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5727531 0.85 MMP12 (0.58) MMP12L3MBTL1POLBTDP1MMP13
SCHEMBL4403318 0.83 MMP12 (0.47) MMP12L3MBTL1POLBTDP1MMP13
SCHEMBL4748340 0.81 MMP12 (0.54) MMP12L3MBTL1POLBTDP1MMP13
SCHEMBL665776 0.81 MMP12 (0.54) MMP12L3MBTL1POLBTDP1MMP13
SCHEMBL4257609 0.80 L3MBTL1 (0.60) MMP12L3MBTL1POLBTDP1MMP13
SCHEMBL5727733 0.78 MMP12 (0.57) MMP12L3MBTL1POLBTDP1MMP13
SCHEMBL7828296 0.78 L3MBTL1 (0.61) L3MBTL1PPARAMMP2PLA2G4B
SCHEMBL6230296 0.78 MMP13 (0.59) MMP12L3MBTL1POLBTDP1MMP13
SCHEMBL667374 0.78 MMP13 (0.59) MMP12L3MBTL1POLBTDP1MMP13
SCHEMBL4613807 0.75 MAPT (0.52) L3MBTL1TDP1MAPK1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615233-B2 Particulate construct comprising polyhydroxyalkanoate and method for producing it CANON KABUSHIKI KAISHA (JP) 2009-11-10 US disclosed
US-7527809-B2 Polyhydroxyalkanoate-containing magnetic structure, and manufacturing method and use thereof CANON KABUSHIKI KAISHA (JP) 2009-05-05 US disclosed
EP-1275378-B1 Particulate construct comprising polyhydroxyalkanoate and method for producing it CANON KK (JP) 2009-04-15 EP disclosed
US-7408017-B2 Polyhydroxyalkanoate containing unit with phenylsulfanyl structure in the side chain, process for its production, charge control agent, toner binder and toner which contain novel polyhydroxyalkanoate, and image forming method and image-forming apparatus which make use of the toner CANON KABUSHIKI KAISHA (JP) 2008-08-05 US disclosed
US-20060263432-A1 Useful as a sustained release pharmaceutical preparation; microcapsule stably containing a drug, especially a water-soluble drug at high content and which has magnetic property; drug delivery; excellent in dispersibility and magnetic response CANON KABUSHIKI KAISHA (JP) 2006-11-23 US disclosed
US-20050250191-A1 Novel polyhydroxyalkanoate containing unit with phenylsulfanyl structure in the side chain, process for its production, charge control agent, toner binder and toner which contain novel polyhydroxyalkanoate, and image forming method and image-forming apparatus which make use of the toner CANON KABUSHIKI KAISHA (JP) 2005-11-10 US disclosed
WO-2004096188-A1 POLYHYDROXYALKANOATE-CONTAINING MAGNETIC STRUCTURE, AND MANUFACTURING METHOD AND USE THEREOF CANON KABUSHIKI KAISHA (JP) 2004-11-11 WO disclosed
US-20030194443-A1 Particulate construct comprising polyhydroxyalkanoate and method for producing it CANON KABUSHIKI KAISHA (JP) 2003-10-16 US disclosed
US-20030013841-A1 Novel polyhydroxyalkanoate containing unit with phenylsulfanyl structure in the side chain, process for its production, charge control agent, toner binder and toner which contain novel polyhydroxyalkanoate, and image-forming method and image-forming apparatus which make use of the toner CANON KABUSHIKI KAISHA (JP) 2003-01-16 US disclosed
EP-1275378-A2 Particulate construct comprising polyhydroxyalkanoate and method for producing it CANON KABUSHIKI KAISHA (JP) 2003-01-15 EP disclosed
EP-1236755-A2 Novel polyhydroxyalkanoate containing unit phenylsulfanyl structure in the side cahin, process for its production, charge control agent, toner binder and toner which contain novel polyhydroxyalkanoate, and imageforming apparatus which make use of the toner CANON KABUSHIKI KAISHA (JP) 2002-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030194443-A1 Particulate construct comprising polyhydroxyalkanoate and method for producing it SQLE, FDFT1, CYP51A1 MMP12 2452/4885L3MBTL1 4037/4885POLB 1038/4885
US-20060263432-A1 Useful as a sustained release pharmaceutical preparation; microcapsule stably containing a drug, especially a water-soluble drug at high content and which has magnetic property; drug delivery; excellent in dispersibility and magnetic response SKP1, HAMP, AUP1 MMP12 1385/4885L3MBTL1 4797/4885POLB 3060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.