Chloroacetic Acid

Chloroacetic Acid

SCHEMBL7828347

N=C1NC(=N)c2ccccc21.O=C(O)CCl

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
TRPA1 O75762 1/20 0.42
MAPK1 P28482 1/20 0.42
GSK3B P49841 1/20 0.42
HIF1A Q16665 1/20 0.42
TSHR P16473 1/20 0.40
APEX1 P27695 1/20 0.39
KMT2A Q03164 4/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
HTT P42858 2/20 0.38
POLB P06746 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PKM P14618 1/20 0.38
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
CDC25B P30305 3/20 0.36
CDC25A P30304 3/20 0.36
AKR1B1 P15121 1/20 0.35
TDP1 Q9NUW8 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL7829045 0.86 APEX1 (0.48) ALDH1A1MAPK1HIF1ATSHRAPEX1
Oxalic Acid SCHEMBL27135274 0.83 THRB (0.40) ALDH1A1MAPK1GSK3BTSHRAPEX1
Oxalic Acid SCHEMBL27003085 0.83 THRB (0.40) ALDH1A1MAPK1GSK3BTSHRAPEX1
Oxalic Acid SCHEMBL30766245 0.83 THRB (0.40) ALDH1A1MAPK1GSK3BTSHRAPEX1
Acetic Acid SCHEMBL27003086 0.81 THRB (0.39) ALDH1A1MAPK1GSK3BTSHRKMT2A
Acetic Acid SCHEMBL7830102 0.81 THRB (0.39) ALDH1A1MAPK1GSK3BTSHRKMT2A
Butyric Acid SCHEMBL7824759 0.79 HDAC3 (0.46) ALDH1A1MAPK1APEX1CDC25BCDC25A
Methoxyacetic Acid SCHEMBL7827617 0.78 POLB (0.42) ALDH1A1MAPK1HIF1ATSHRAPEX1
Benzoic Acid SCHEMBL7827449 0.78 TSHR (0.58) ALDH1A1TRPA1TSHRPKMCA12
Phthalic Acid SCHEMBL18663463 0.78 ALDH1A1 (0.58) ALDH1A1POLBCA12CA9CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed