Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827224 | 0.81 | KDM4E (0.49) | ALDH1A1TSHRKDM4EHSD17B10CNR1 | |
| SCHEMBL8345547 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EHSD17B10CNR1 | |
| SCHEMBL7826306 | 0.78 | GAA (0.45) | ALDH1A1THRBKMT2ANPSR1POLB | |
| SCHEMBL7831814 | 0.76 | RAB9A (0.42) | ALDH1A1THRBKMT2ANPSR1POLB | |
| SCHEMBL7829002 | 0.76 | RAB9A (0.48) | ALDH1A1TSHRCNR1CNR2KMT2A | |
| SCHEMBL8800008 | 0.76 | P2RX7 (0.42) | ALDH1A1TSHRKDM4EHSD17B10CNR1 | |
| SCHEMBL7823933 | 0.75 | MAPT (0.48) | ALDH1A1THRBKMT2ANPSR1POLB | |
| SCHEMBL8341651 | 0.75 | RAB9A (0.45) | ALDH1A1TSHRKDM4EHSD17B10CNR1 | |
| SCHEMBL7828069 | 0.75 | GPR35 (0.46) | ALDH1A1KDM4EKMT2ANPSR1POLB | |
| SCHEMBL8341922 | 0.75 | GPR35 (0.42) | ALDH1A1THRBKMT2ANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |