Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062311 | 0.83 | IDO1 (0.70) | IDO1AKR1C3TSHRLOXL2CA12 | |
| SCHEMBL37463 | 0.83 | IDO1 (0.70) | IDO1AKR1C3TSHRLOXL2CA12 | |
| SCHEMBL293414 | 0.79 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2CA12 | |
| SCHEMBL21753899 | 0.79 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2CA12 | |
| SCHEMBL293415 | 0.79 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2CA12 | |
| SCHEMBL23091915 | 0.79 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2CA12 | |
| SCHEMBL12417032 | 0.79 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2CA12 | |
| SCHEMBL4016592 | 0.79 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2CA12 | |
| SCHEMBL7769668 | 0.79 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2CA12 | |
| SCHEMBL1722787 | 0.79 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366560-A1 | Tylosin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1990-05-02 | — | — | EP | claimed |
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |
| EP-0553119-A1 | HETEROCYCLIC COMPOUNDS | ZENECA LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |
| US-5192777-A | Antibiotics | AMERICAN CYANAMID COMPANY (US) | 1993-03-09 | — | — | US | disclosed |
| US-5187176-A | 1-PHENYL SUBSTITUTED PYRIMIDONE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-16 | — | — | US | disclosed |
| WO-1992006964-A1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-30 | — | — | WO | disclosed |
| US-5109004-A | Cyano phenyl-substituted with heterocylic compound; insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-28 | — | — | US | disclosed |
| US-5039807-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-08-13 | — | — | US | disclosed |
| EP-0398499-A2 | Insecticides | ZENECA LIMITED (GB) | 1990-11-22 | — | — | EP | disclosed |
| EP-0367410-A1 | Aryl pyridones as insecticidal agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-09 | — | — | EP | disclosed |
| US-4866078-A | Phenyl pyridones and insectidal use thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-12 | — | — | US | disclosed |
| EP-0307225-A2 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |