Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293414 | 0.83 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL37463 | 0.83 | IDO1 (0.70) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL8062311 | 0.83 | IDO1 (0.70) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL4985766 | 0.80 | TSHR (0.58) | IDO1AKR1C3LOXL2TSHRCYP2C19 | |
| SCHEMBL23091915 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL21753899 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL7769668 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL4016592 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL12417032 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL7829129 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025514-A1 | COMPOUNDS USEFUL AS ANXIOLYTIC, SEDATIVE, AND HYPNOTIC AGENTS | DISCOVERY THERAPEUTICS, INC. (US) | 1995-09-28 | — | — | WO | claimed |
| US-20240189486-A1 | ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF | UNIVERSITÉ DE BORDEAUX (FR) | 2024-06-13 | — | — | US | disclosed |
| EP-4294821-A1 | ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF | UNIVERSITE DE BORDEAUX (FR) | 2023-12-27 | — | — | EP | disclosed |
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| EP-4047012-A1 | ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF | Université de Bordeaux (FR) | 2022-08-24 | — | — | EP | disclosed |
| US-20220211802-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-07-07 | — | — | US | disclosed |
| US-20220162183-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC | 2022-05-26 | — | — | US | disclosed |
| US-11331369-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3790876-A1 | ENDOPARASITIC DEPSIPEPTIDES | Zoetis Services LLC (US) | 2021-03-17 | — | — | EP | disclosed |
| WO-1999025752-A1 | FUNCTIONALIZED RESIN FOR THE SYNTHESIS OF AMIDES AND PEPTIDES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-05-27 | — | — | WO | disclosed |
| WO-1999019294-A1 | PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES | AVENTIS PHARMACEUTICALS PRODUCTS INC. LEGAL/PATENTS (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1998029376-A1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES, OXIMES, AMINES AND HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-07-09 | — | — | WO | disclosed |
| WO-1998017678-A1 | ANTITHROMBOTIC AZACYCLOALKYLALKANOYL PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-04-30 | — | — | WO | disclosed |
| WO-1998007696-A1 | STABLE NON-HYGROSCOPIC CRYSTALLINE FORM OF N-[N-N-(4-(PIPERIDIN-4-YL)BUTANOYL)-N-ETHYLGLYCYL] COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-26 | — | — | WO | disclosed |
| EP-0297456-A2 | Immunosuppressant peptides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-01-04 | — | — | EP | disclosed |
| EP-0252885-A1 | Bicyclic thiaaza compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |
| EP-0239853-A1 | 3,4-Disubstituted-2-azetidinone derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4365062-A | BACTERICIDAL ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-21 | — | — | US | disclosed |
| US-4060688-A | Cephalosporin intermediates | ELI LILLY AND COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162183-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | HTR2B, HTR1B, HTR5A | IDO1 1019/4885AKR1C3 3817/4885LOXL2 1063/4885 |
| US-11786575-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | IDO1 540/4885AKR1C3 1119/4885LOXL2 1984/4885 |
| US-20220211802-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | IDO1 540/4885AKR1C3 1119/4885LOXL2 1984/4885 |
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | IDO1 455/4885AKR1C3 918/4885LOXL2 1694/4885 |
| US-11331369-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | IDO1 540/4885AKR1C3 1119/4885LOXL2 1984/4885 |
| US-20240189486-A1 | ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF | NGLY1, VIP, FPR3 | IDO1 2757/4885AKR1C3 3859/4885LOXL2 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.