Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722787 | 0.83 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL37463 | 0.83 | IDO1 (0.70) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL8062311 | 0.83 | IDO1 (0.70) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL3157211 | 0.80 | IDO1 (0.61) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL7057603 | 0.80 | TSHR (0.58) | IDO1AKR1C3LOXL2TSHRALDH1A1 | |
| SCHEMBL23091915 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL21753899 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL7769668 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL12417032 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL4016592 | 0.79 | IDO1 (0.66) | IDO1AKR1C3LOXL2TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 641 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046663-B2 | Entecavir intermediate, synthetic method thereof and synthetic method for entecavir | LAUNCH-PHARMA TECHNOLOGIES, LTD. (CN) | 2021-06-29 | — | — | US | claimed |
| CN-109705063-B | Entecavir intermediate and synthetic method thereof, and synthetic method of entecavir | 广州市朗启医药科技有限责任公司 | 2021-01-01 | — | — | CN | claimed |
| US-20200255390-A1 | ENTECAVIR INTERMEDIATE, SYNTHETIC METHOD THEREOF AND SYNTHETIC METHOD FOR ENTECAVIR | LAUNCH-PHARMA TECHNOLOGIES, LTD. (CN) | 2020-08-13 | — | — | US | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| EP-3323414-A1 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2018-05-23 | — | — | EP | claimed |
| EP-2727915-B1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | CONCERT PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | claimed |
| EP-2508504-B1 | PROCESS FOR PREPARATION OF CYCLOALKANEDICARBOXYLIC ACID MONOESTERS | SUMITOMO CHEMICAL CO (JP) | 2016-04-13 | — | — | EP | claimed |
| EP-2727915-A1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | Concert Pharmaceuticals Inc. (US) | 2014-05-07 | — | — | EP | claimed |
| US-8343893-B2 | Substituted enaminocarbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2013-01-01 | — | — | US | claimed |
| EP-2508504-A1 | PROCESS FOR PREPARATION OF CYCLOALKANEDICARBOXYLIC ACID MONOESTERS | Sumitomo Chemical Co., Ltd (JP) | 2012-10-10 | — | — | EP | claimed |
| WO-2010145764-A1 | SUBSTITUTED ENAMINO CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2010-12-23 | — | — | WO | claimed |
| EP-2264008-A1 | Substituted enaminocarbonyl compounds | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | claimed |
| EP-1594835-A4 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS INC (US) | 2007-05-02 | — | — | EP | claimed |
| EP-1740522-A2 | BISPHENYL COMPOUNDS USEFUL AS VITAMIN D SB 3 /SB RECEPTOR AGONISTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-01-10 | — | — | EP | claimed |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | HONG BORCHERNG | 2006-08-03 | — | — | US | claimed |
| US-20060025474-A1 | Bisphenyl compounds useful as vitamin D3 receptor agonists | CHUGAI SEIYAKU KABUSHIKA KAISHA (JP) | 2006-02-02 | — | — | US | claimed |
| EP-1594835-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | Auspex Pharmaceuticals, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2005087700-A2 | BISPHENYL COMPOUNDS USEFUL AS VITAMIN D3 RECEPTOR AGONISTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-09-22 | — | — | WO | claimed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | claimed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025474-A1 | Bisphenyl compounds useful as vitamin D3 receptor agonists | VDR, CYP2R1, CYP24A1 | IDO1 3331/4885AKR1C3 182/4885LOXL2 2573/4885 |
| US-20200255390-A1 | ENTECAVIR INTERMEDIATE, SYNTHETIC METHOD THEREOF AND SYNTHETIC METHOD FOR ENTECAVIR | ENTPD5, SAMHD1, ENTPD8 | IDO1 1043/4885AKR1C3 1860/4885LOXL2 4410/4885 |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | LSS, DHPS, CYP51A1 | IDO1 1322/4885AKR1C3 1516/4885LOXL2 2154/4885 |
| US-11046663-B2 | Entecavir intermediate, synthetic method thereof and synthetic method for entecavir | ENTPD5, SAMHD1, ENTPD8 | IDO1 1043/4885AKR1C3 1860/4885LOXL2 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.