Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2843886 | 0.84 | CA12 (0.56) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL1663647 | 0.82 | CA2 (0.58) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL11290600 | 0.82 | CYP1A2 (0.60) | MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL1689279 | 0.82 | KDM1A (0.69) | MEN1KMT2AKDM1AGAA | |
| SCHEMBL2560745 | 0.81 | MAPT (0.66) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL9912437 | 0.80 | CA12 (0.56) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL4337756 | 0.80 | PEPD (0.63) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL7521048 | 0.79 | PEPD (0.61) | CA2MEN1KMT2AALDH1A1CA1 | |
| SCHEMBL5192063 | 0.79 | POLB (0.57) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL7821936 | 0.79 | KMT2A (0.58) | CA12CA2CA9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |