Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145987 | 0.87 | MAPT (0.72) | KDM1AL3MBTL1EPHX2MAPTTSHR | |
| SCHEMBL1689206 | 0.86 | EPHX2 (0.68) | KDM1AL3MBTL1EPHX2MAPTHTT | |
| SCHEMBL28051723 | 0.85 | KDM1A (0.67) | KDM1AL3MBTL1EPHX2MAPTHTT | |
| SCHEMBL3075021 | 0.83 | KDM1A (0.65) | KDM1AL3MBTL1EPHX2MAPTHTT | |
| SCHEMBL3353284 | 0.83 | L3MBTL1 (0.72) | KDM1AL3MBTL1EPHX2MAPTHTT | |
| SCHEMBL175602 | 0.82 | EPHX2 (0.63) | KDM1AL3MBTL1EPHX2MAPTHTT | |
| SCHEMBL27538195 | 0.82 | EPHX2 (0.63) | KDM1AL3MBTL1EPHX2MAPTHTT | |
| SCHEMBL7829396 | 0.82 | CA12 (0.53) | KDM1AGAAMEN1KMT2A | |
| Iodoacetamide SCHEMBL21543900 | 0.82 | KDM1A (0.58) | KDM1AL3MBTL1EPHX2MAPTHTT | |
| Hydrochloric Acid SCHEMBL3353961 | 0.82 | L3MBTL1 (0.70) | KDM1AL3MBTL1EPHX2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693529-A | Synthesis method of 2-aza [2.2.2] octane compound | 河南师范大学 | 2023-09-05 | — | — | CN | claimed |
| CN-101796055-B | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE INC | 2013-09-04 | — | — | CN | claimed |
| EP-1971600-B1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-08-21 | — | — | EP | claimed |
| US-20090131336-A1 | Isoxazole Derivatives and Use Thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-05-21 | — | — | US | claimed |
| EP-1971600-A1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK Holdings Co., Ltd. (KR) | 2008-09-24 | — | — | EP | claimed |
| EP-1957498-A2 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | MethylGene Inc. (CA) | 2008-08-20 | — | — | EP | claimed |
| WO-2008041053-A2 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE, INC. (CA) | 2008-04-10 | — | — | WO | claimed |
| EP-1896395-A2 | MODIFIED MALONATE DERIVATIVES | Merck & Co., Inc. (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2007078113-A1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2007-07-12 | — | — | WO | claimed |
| WO-2007002248-A2 | MODIFIED MALONATE DERIVATIVES | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE, INC. | 2007-01-04 | — | — | US | claimed |
| EP-0384670-A2 | Method for processing light sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1990-08-29 | — | — | EP | claimed |
| EP-0383623-A2 | Light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1990-08-22 | — | — | EP | claimed |
| EP-0365282-A2 | A silver halide colour photographic light-sensitive material | KONICA CORPORATION (JP) | 1990-04-25 | — | — | EP | claimed |
| CN-117946032-A | Novel efficient preparation method of acrylamide compound | 深圳有为技术控股集团有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117777059-A | Preparation method of acrylamide compound | 深圳有为技术控股集团有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117050037-A | Preparation method of acrylamide compound | 深圳有为技术控股集团有限公司 | 2023-11-14 | — | — | CN | disclosed |
| EP-0012112-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | disclosed |
| US-4291901-A | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |
| EP-0012112-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | HGF, MET, FLT1 | KDM1A 4241/4885L3MBTL1 4202/4885EPHX2 2959/4885 |
| US-20090131336-A1 | Isoxazole Derivatives and Use Thereof | WNT3A, WNT1, WNT3 | KDM1A 4612/4885L3MBTL1 4026/4885EPHX2 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.