Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069058 | 1.00 | IP6K1 (0.46) | IP6K1FGFR1NPC1RAB9AKMT2A | |
| Trifluoroacetic Acid SCHEMBL8068251 | 0.92 | IP6K1 (0.39) | IP6K1FGFR1NPC1RAB9AKMT2A | |
| SCHEMBL8058059 | 0.86 | ALDH1A1 (0.41) | IP6K1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8058054 | 0.86 | ALDH1A1 (0.41) | IP6K1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8073563 | 0.84 | GLA (0.42) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL8073556 | 0.84 | GLA (0.42) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL8073308 | 0.84 | IP6K1 (0.41) | IP6K1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8073292 | 0.84 | IP6K1 (0.41) | IP6K1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8066788 | 0.83 | PADI4 (0.40) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL7825535 | 0.80 | KIF11 (0.43) | PARP1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |