Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 2/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCND3 | P30281 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073308 | 1.00 | IP6K1 (0.41) | IP6K1TTKCHEK1CDK4CCNA2 | |
| Trifluoroacetic Acid SCHEMBL8057444 | 0.91 | IP6K1 (0.35) | IP6K1CHEK1TOP2AKDM1AHDAC1 | |
| SCHEMBL8066788 | 0.86 | PADI4 (0.40) | TTKMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8069062 | 0.84 | IP6K1 (0.46) | IP6K1CHEK1MAPTALDH1A1NPC1 | |
| SCHEMBL8069058 | 0.84 | IP6K1 (0.46) | IP6K1CHEK1MAPTALDH1A1NPC1 | |
| SCHEMBL7825535 | 0.84 | KIF11 (0.43) | TTKCHEK1PARP1CSNK2A1 | |
| SCHEMBL7825711 | 0.83 | CCNB2 (0.37) | CHEK1CDK1 | |
| SCHEMBL7825041 | 0.82 | CCNB2 (0.33) | CDK1 | |
| SCHEMBL7829829 | 0.82 | CCNB2 (0.33) | CDK1 | |
| SCHEMBL7825038 | 0.82 | CCNB2 (0.33) | CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |