Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831632 | 0.89 | BRD4 (0.42) | PDE2ATP53KDM4EALDH1A1HPGD | |
| SCHEMBL5453718 | 0.82 | TP53 (0.58) | PDE2ATP53KDM4EALDH1A1HPGD | |
| SCHEMBL7827833 | 0.82 | KDM4E (0.56) | PDE2ATP53KDM4EALDH1A1HPGD | |
| SCHEMBL7831493 | 0.80 | CDK2 (0.54) | TP53KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL7819484 | 0.76 | TP53 (0.59) | TP53KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL7830946 | 0.76 | TP53 (0.48) | TP53KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL7833669 | 0.74 | GSK3B (0.57) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7819164 | 0.73 | TP53 (0.49) | TP53KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL5468155 | 0.73 | KCNN3 (0.55) | PDE2ATP53KDM4EALDH1A1HPGD | |
| SCHEMBL5456353 | 0.73 | KCNN3 (0.52) | PDE2ATP53KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | claimed |
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | disclosed |