Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819164 | 0.91 | TP53 (0.49) | TP53KCNN3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7829399 | 0.89 | TP53 (0.48) | TP53KCNN3MEN1KMT2AHPGD | |
| SCHEMBL7819220 | 0.78 | KDM4E (0.58) | TP53SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7831493 | 0.76 | CDK2 (0.54) | TP53SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7830106 | 0.76 | PDE2A (0.48) | TP53SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7830853 | 0.75 | F2 (0.48) | TP53SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7833669 | 0.75 | GSK3B (0.57) | TP53SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7827833 | 0.74 | KDM4E (0.56) | TP53SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7830946 | 0.74 | TP53 (0.48) | TP53MEN1KMT2AHPGDLMNA | |
| SCHEMBL7827676 | 0.72 | ALDH1A1 (0.47) | TP53MEN1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | claimed |
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | disclosed |