Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 6/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831493 | 0.86 | CDK2 (0.54) | GSK3BKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL12954031 | 0.81 | GSK3B (0.67) | GSK3BKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7819220 | 0.79 | KDM4E (0.58) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL7830853 | 0.78 | F2 (0.48) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL7831500 | 0.76 | TUBB4A (0.48) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL7827676 | 0.76 | ALDH1A1 (0.47) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL7819484 | 0.75 | TP53 (0.59) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL30457108 | 0.74 | BRD4 (0.48) | GSK3BKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7830106 | 0.74 | PDE2A (0.48) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL7831632 | 0.74 | BRD4 (0.42) | KDM4EHSD17B10CDK2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | claimed |
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | disclosed |