Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30457108 | 0.89 | BRD4 (0.48) | CDK2BRD4LMNATP53MAPT | |
| SCHEMBL7833669 | 0.86 | GSK3B (0.57) | CDK2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL7830106 | 0.80 | PDE2A (0.48) | BRD4LMNAAURKACSF1RRET | |
| SCHEMBL7819220 | 0.80 | KDM4E (0.58) | AURKACSF1RRETLTKCSNK1A1 | |
| SCHEMBL7831632 | 0.80 | BRD4 (0.42) | CDK2BRD4LMNAAURKACSF1R | |
| SCHEMBL7830853 | 0.77 | F2 (0.48) | LMNAAURKACSF1RRETLTK | |
| SCHEMBL7819484 | 0.76 | TP53 (0.59) | LMNAAURKACSF1RRETLTK | |
| SCHEMBL7831500 | 0.75 | TUBB4A (0.48) | LMNAAURKACSF1RRETLTK | |
| SCHEMBL7827676 | 0.74 | ALDH1A1 (0.47) | LMNAAURKACSF1RRETLTK | |
| SCHEMBL7827833 | 0.74 | KDM4E (0.56) | LMNATP53MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | claimed |
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | disclosed |