Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | PRCP | P42785 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709300 | 0.75 | SLC22A1 (0.59) | SLC22A1PRCPADRB2GRIN2BHTR2A | |
| SCHEMBL5691995 | 0.72 | PRCP (0.63) | SLC22A1PRCPADRB2GRIN2BHTR2A | |
| SCHEMBL27959648 | 0.68 | SLC22A1 (0.57) | SLC22A1PRCPADRB2GRIN2BHTR2A | |
| SCHEMBL5812041 | 0.68 | PRCP (1.00) | SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL29768314 | 0.68 | PRCP (1.00) | SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL4160731 | 0.68 | PRCP (1.00) | SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL5284097 | 0.68 | PRCP (1.00) | SLC22A1PRCPADRB2KDM1A | |
| Water SCHEMBL28203568 | 0.67 | PRCP (0.97) | SLC22A1PRCPADRB2KDM1A | |
| Hydrochloric Acid SCHEMBL8823234 | 0.67 | PRCP (0.97) | SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL10349434 | 0.65 | ADRB2 (0.72) | SLC22A1PRCPADRB2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888332-B1 | N-Azacycloalkyl Alkyl Dibenzothiophene Carboxamides: Dopamine Receptor Subtype Specific Ligands | NEUROGEN CORP (US) | 2001-05-30 | — | — | EP | disclosed |