Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27959648 | 0.80 | SLC22A1 (0.57) | PRCPSLC22A1ADRB2GRIN2BKDM1A | |
| SCHEMBL5812041 | 0.78 | PRCP (1.00) | PRCPSLC22A1ADRB2KDM1A | |
| SCHEMBL29768314 | 0.78 | PRCP (1.00) | PRCPSLC22A1ADRB2KDM1A | |
| SCHEMBL4160731 | 0.78 | PRCP (1.00) | PRCPSLC22A1ADRB2KDM1A | |
| SCHEMBL5284097 | 0.78 | PRCP (1.00) | PRCPSLC22A1ADRB2KDM1A | |
| Water SCHEMBL28203568 | 0.76 | PRCP (0.97) | PRCPSLC22A1ADRB2KDM1A | |
| Hydrochloric Acid SCHEMBL8823234 | 0.76 | PRCP (0.97) | PRCPSLC22A1ADRB2KDM1A | |
| SCHEMBL7830263 | 0.72 | SLC22A1 (0.51) | PRCPSLC22A1ADRB2GRIN2BKDM1A | |
| SCHEMBL8556154 | 0.71 | DRD2 (0.48) | PRCPSLC22A1ADRB2KDM1A | |
| SCHEMBL10349433 | 0.71 | ADRB2 (0.72) | PRCPSLC22A1ADRB2KDM1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641760-A2 | NOVEL TETRAHYDROQUINOLINES | Pfizer Products Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| WO-2004108682-A2 | TETRAHYDROISOQUINOLINES AS ANTAGONISTS OF THE 5HT1B RECEPTOR | PFIZER PRODUCTS INC. (US) | 2004-12-16 | — | — | WO | disclosed |