SCHEMBL7830951

SCHEMBL7830951

Cc1ccc(Nc2ccccc2O)cc1.Cc1cccc(Nc2ccccc2O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.58
MAPT P10636 7/20 0.49
HPGD P15428 4/20 0.49
CXCR2 P25025 3/20 0.49
GAA P10253 5/20 0.49
TDP1 Q9NUW8 1/20 0.49
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPK13 O15264 1/20 0.45
MAPK12 P53778 1/20 0.45
MAPK11 Q15759 1/20 0.45
MAPK14 Q16539 1/20 0.45
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6882349 0.93 NPSR1 (0.60) NPSR1MAPTHPGDCXCR2GAA
SCHEMBL5823760 0.88 MAPT (0.60) NPSR1MAPTHPGDCXCR2GAA
SCHEMBL30686692 0.88 MAPT (0.60) NPSR1MAPTHPGDCXCR2GAA
SCHEMBL17063545 0.86 HPGD (0.59) NPSR1MAPTHPGDCXCR2GAA
SCHEMBL17526960 0.83 CXCR2 (0.58) NPSR1MAPTHPGDCXCR2GAA
SCHEMBL4568692 0.81 NFKB1 (0.56) NPSR1MAPTHPGDGAANPC1
SCHEMBL1922073 0.80 NPSR1 (0.72) NPSR1MAPTMEN1KMT2AALDH1A1
SCHEMBL11502241 0.80 NPSR1 (0.79) NPSR1MAPTHPGDGAATDP1
SCHEMBL3040701 0.80 NPSR1 (0.79) NPSR1MAPTHPGDGAATDP1
SCHEMBL1920750 0.78 CXCR2 (0.59) NPSR1MAPTHPGDCXCR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1107972-A1 PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN Ciba SC Holding AG (CH) 2001-06-20 EP disclosed
WO-2000012513-A1 NOVEL PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed