Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820393 | 0.88 | MEN1 (0.44) | PKMKMT2AMEN1PSMB5PPARG | |
| SCHEMBL22394804 | 0.76 | ESR1 (0.65) | ATML3MBTL1PKMKMT2AMEN1 | |
| SCHEMBL7820917 | 0.74 | L3MBTL1 (0.45) | ATML3MBTL1PKMKMT2AMEN1 | |
| SCHEMBL7831378 | 0.72 | PPARG (0.52) | ATML3MBTL1PKMPPARGPPARA | |
| SCHEMBL5424343 | 0.71 | LMNA (0.54) | L3MBTL1PKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22394826 | 0.70 | SMN1; SMN2 (0.56) | KMT2AMEN1PSMB5PPARGPPARA | |
| SCHEMBL16327191 | 0.69 | PTPRB (0.59) | ATML3MBTL1PPARGPPARAESR1 | |
| SCHEMBL6054516 | 0.69 | ATM (0.48) | ATMKMT2AMEN1 | |
| SCHEMBL1855181 | 0.69 | ATM (0.48) | ATML3MBTL1KMT2AMEN1PPARG | |
| SCHEMBL7896758 | 0.69 | PPARG (0.53) | KMT2AMEN1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460488-B1 | Sulfur-containing heterocyclic compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5158943-A | Osteoporosis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0460488-A1 | Sulfur-containing heterocyclic compounds | Takeda Chemical Industries, Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |