Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880383 | 0.86 | MMP8 (0.52) | ALDH1A1HSD17B10MEN1KMT2APOLB | |
| SCHEMBL9395388 | 0.86 | ALDH1A1 (0.46) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7820917 | 0.86 | L3MBTL1 (0.45) | ATMALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4842827 | 0.83 | ALPI (0.53) | CYP2C9CYP2C19HSD17B10MEN1KMT2A | |
| SCHEMBL839467 | 0.83 | ALPI (0.53) | CYP2C9CYP2C19HSD17B10MEN1KMT2A | |
| SCHEMBL839468 | 0.83 | ALPI (0.53) | CYP2C9CYP2C19HSD17B10MEN1KMT2A | |
| SCHEMBL8255515 | 0.81 | ALDH1A1 (0.45) | ALDH1A1CYP2C9CYP2C19HSD17B10MEN1 | |
| SCHEMBL1855181 | 0.81 | ATM (0.48) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL27517162 | 0.80 | ALDH1A1 (0.57) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL10956811 | 0.80 | BIRC2 (0.60) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247470-A1 | Process for producing optically active carboxylic acid substituted in 2-position | KANEKA CORPORATION | 2006-11-02 | — | — | US | disclosed |
| US-7094926-B2 | Process for producing optically active carboxylic acid substituted in 2-position | KANEKA CORPORATION (JP) | 2006-08-22 | — | — | US | disclosed |
| US-20030144546-A1 | Process for producing optically active carboxylic acid subtituted in 2-position | KANEKA CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| US-20030013903-A1 | Process for crystallization of 2-acetylthio-3-phenyl-propionic acid | KANEKA CORPORATION (JP) | 2003-01-16 | — | — | US | disclosed |
| EP-1275642-A1 | PROCESS FOR CRYSTALLIZATION OF 2-ACETYLTHIO-3-PHENYL-PROPIONIC ACID | KANEKA CORPORATION (JP) | 2003-01-15 | — | — | EP | disclosed |
| EP-1251115-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID SUBSTITUTED IN 2-POSITION | KANEKA CORPORATION (JP) | 2002-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144546-A1 | Process for producing optically active carboxylic acid subtituted in 2-position | HAO2, CA2, HACL2 | ATM 1752/4885ALDH1A1 374/4885THRB 827/4885 |
| US-20060247470-A1 | Process for producing optically active carboxylic acid substituted in 2-position | HAO2, CA2, HACL2 | ATM 1894/4885ALDH1A1 558/4885THRB 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.