Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832665 | 0.92 | CBFB (0.49) | F9IDH1CBFBCYP19A1CYP11B1 | |
| SCHEMBL7830643 | 0.91 | MAOA (0.42) | F9IDH1CBFBCYP19A1CYP11B1 | |
| SCHEMBL7834212 | 0.85 | MAOA (0.45) | F9IDH1CBFBCYP19A1CYP11B1 | |
| SCHEMBL7822768 | 0.84 | IDH1 (0.48) | F9IDH1CBFBCYP19A1CYP11B1 | |
| SCHEMBL7831669 | 0.83 | F9 (0.40) | F9IDH1CBFBCYP19A1CYP11B1 | |
| SCHEMBL7830649 | 0.83 | MAOA (0.44) | F9CBFBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7833040 | 0.81 | CBFB (0.42) | F9CBFBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7833717 | 0.81 | F9 (0.41) | F9CBFBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7833055 | 0.80 | F9 (0.42) | F9CBFBCYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8155236 | 0.78 | F9 (0.46) | F9IDH1CBFBCYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |