Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.44 |
| ▸ | ITGAV | P06756 | 12/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338950 | 0.85 | HSD17B10 (0.56) | ITGB1HSD17B10ITGA4MEN1KMT2A | |
| SCHEMBL7843541 | 0.82 | MEN1 (0.40) | ITGB3ITGAVITGB1ITGA5HSD17B10 | |
| SCHEMBL6783293 | 0.79 | HSD17B10 (0.54) | HSD17B10MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL7377590 | 0.78 | GSK3B (0.58) | ITGB3ITGAVITGB1HSD17B10ITGA4 | |
| SCHEMBL7835493 | 0.78 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL7833496 | 0.77 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5KMT2A | |
| SCHEMBL7337671 | 0.77 | GPR132 (0.54) | EPHX2 | |
| SCHEMBL7832738 | 0.73 | GPR132 (0.47) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7823055 | 0.73 | ITGB3 (0.43) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL6778765 | 0.73 | HSD17B10 (0.55) | HSD17B10MEN1KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-B1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2001-07-18 | — | — | EP | claimed |