Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 12/20 | 0.48 |
| ▸ | PLAU | P00749 | 10/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842910 | 0.70 | LMNA (0.56) | LMNASMN1; SMN2 | |
| SCHEMBL4040020 | 0.67 | GAA (0.52) | HPNPLAUMMP9ALDH1A1HSD17B10 | |
| SCHEMBL7835649 | 0.67 | GAA (0.52) | HPNPLAUMMP9ALDH1A1HSD17B10 | |
| SCHEMBL14011605 | 0.67 | GAA (0.52) | HPNPLAUMMP9ALDH1A1HSD17B10 | |
| SCHEMBL28560480 | 0.66 | KMT2A (0.55) | MMP9ALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL28554116 | 0.66 | GAA (0.55) | MMP9ALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL30988968 | 0.66 | GAA (0.55) | MMP9ALDH1A1HSD17B10HPGDLMNA | |
| Hydrochloric Acid SCHEMBL7347096 | 0.66 | GAA (0.51) | HPNPLAUMMP9ALDH1A1HSD17B10 | |
| SCHEMBL9272964 | 0.65 | CA2 (0.50) | HPNPLAUMMP9ALDH1A1HSD17B10 | |
| SCHEMBL25961785 | 0.65 | CA2 (0.50) | HPNPLAUMMP9ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023295-A4 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | MERCK & CO INC (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-1023295-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | Merck & Co., Inc. (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1998034935-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | MERCK & CO., INC. (US) | 1998-08-13 | — | — | WO | disclosed |