Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954 | 0.84 | F2 (0.58) | PRSS1PRSS2PRSS3C1SRECQL | |
| SCHEMBL27411702 | 0.84 | F2 (0.58) | PRSS1PRSS2PRSS3C1SRECQL | |
| Ammonia Solution, Strong SCHEMBL28070268 | 0.81 | F2 (0.55) | PRSS1PRSS2PRSS3C1SRECQL | |
| SCHEMBL10607595 | 0.81 | F2 (0.55) | PRSS1PRSS2PRSS3C1SRECQL | |
| Hydrochloric Acid SCHEMBL30040932 | 0.81 | BLM (0.60) | PRSS1PRSS2PRSS3C1SRECQL | |
| SCHEMBL28001024 | 0.81 | F2 (0.55) | PRSS1PRSS2PRSS3C1SRECQL | |
| Hydrochloric Acid SCHEMBL18795794 | 0.81 | BLM (0.60) | PRSS1PRSS2PRSS3C1SRECQL | |
| SCHEMBL4578344 | 0.81 | F2 (0.55) | PRSS1PRSS2PRSS3C1SRECQL | |
| SCHEMBL10606109 | 0.79 | TSHR (0.54) | PRSS1PRSS2PRSS3C1SRECQL | |
| SCHEMBL27279692 | 0.79 | F2 (0.48) | PRSS1PRSS2PRSS3C1SRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57130972-A | — | — | None | — | — | JP | disclosed |
| EP-4665717-A2 | USES OF CERTAIN 1,4-OXAZEPANE-2-CARBOXAMIDES AS DPP1 INHIBITORS | Insmed Incorporated (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250250232-A1 | AZETIDINE DERIVATIVES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-08-07 | — | — | US | disclosed |
| US-12365673-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2025-07-22 | — | — | US | disclosed |
| EP-4538271-A1 | POLYMORPH OF BENZO[C]CHROMAN COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Reistone Biopharma Company Limited (CN) | 2025-04-16 | — | — | EP | disclosed |
| EP-4538277-A1 | PHARMACEUTICALLY ACCEPTABLE SALT OF BENZO[C]CHROMAN COMPOUND AND POLYMORPHIC FORM AND USE OF PHARMACEUTICALLY ACCEPTABLE SALT | Reistone Biopharma Company Limited (CN) | 2025-04-16 | — | — | EP | disclosed |
| EP-4497473-A2 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | Haisco Pharmaceuticals Pte. Ltd. (SG) | 2025-01-29 | — | — | EP | disclosed |
| EP-4129989-B1 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | HAISCO PHARMACEUTICALS PTE LTD (SG) | 2024-10-02 | — | — | EP | disclosed |
| WO-2024173556-A2 | USES OF CERTAIN 1,4-OXAZEPANE-2-CARBOXAMIDES AS DPP1 INHIBITORS | INSMED INCORPORATED (US) | 2024-08-22 | — | — | WO | disclosed |
| US-20240083888-A1 | SMALL MOLECULE INHIBITOR FOR CATHEPSIN C AND MEDICINAL USE THEREOF | REISTONE BIOPHARMA COMPANY LIMITED (CN) | 2024-03-14 | — | — | US | disclosed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |
| WO-2000051976-A1 | REGIOSELECTIVE SYNTHESIS OF DTPA DERIVATIVES | IDEC PHARMACEUTICALS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
| EP-1028942-A2 | DIPEPTIDE NITRILES | Novartis AG (CH) | 2000-08-23 | — | — | EP | disclosed |
| US-6093727-A | A SELECTIVE AGONISTS FOR HUMAN ALPHA 2 RECEPTORS FOR TREATING DISORDERS AS HYPERTENSION, PAIN, GLAUCOMA, ALCOHOL AND DRUG WITHDRAWAL, ISCHEMIA, RHEUMATOID ARTHRITIS, MIGRAINE, COGNITIVE DEFICIENCY, SPASTICITY, DIARRHEA, NASAL CONGESTION | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-07-25 | — | — | US | disclosed |
| WO-1999024460-A2 | DIPEPTIDE NITRILES | NOVARTIS AG (CH) | 1999-05-20 | — | — | WO | disclosed |
| US-5866579-A | SELECTIVE AGONISTS FOR CLONED HUMAN ALPHA-2 ADRENERGIC RECEPTORS. | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0037271-B1 | INDOLE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | TORAY INDUSTRIES, INC. (JP) | 1984-01-18 | — | — | EP | disclosed |
| US-4399289-A | STABLE TRYPTOPHANE INTERMEDIATES | TORAY INDUSTRIES, INC. (JP) | 1983-08-16 | — | — | US | disclosed |
| JP-S57130972-A | PREPARATION OF INDOLE DERIVATIVE | TORAY IND INC | 1982-08-13 | — | — | JP | disclosed |
| EP-0037271-A1 | Indole derivatives and process for preparing the same | TORAY INDUSTRIES, INC. (JP) | 1981-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365673-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | DPP4, DPP3, DPP9 | PRSS1 30/4885PRSS2 97/4885PRSS3 42/4885 |
| US-20240083888-A1 | SMALL MOLECULE INHIBITOR FOR CATHEPSIN C AND MEDICINAL USE THEREOF | CTSF, CTSV, CTSB | PRSS1 160/4885PRSS2 217/4885PRSS3 148/4885 |
| US-20250250232-A1 | AZETIDINE DERIVATIVES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS | DPP9, DPP4, DPP3 | PRSS1 47/4885PRSS2 191/4885PRSS3 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.