Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835223 | 1.00 | ARG1 (0.40) | ARG1ALDH1A1TSHRTLR8ESR1 | |
| SCHEMBL7838436 | 0.73 | TSHR (0.41) | ALDH1A1TSHRKMT2AMEN1HTT | |
| SCHEMBL7838433 | 0.73 | TSHR (0.41) | ALDH1A1TSHRKMT2AMEN1HTT | |
| SCHEMBL7837929 | 0.72 | CYP11B1 (0.59) | ALDH1A1 | |
| SCHEMBL7837924 | 0.72 | CYP11B1 (0.59) | ALDH1A1 | |
| SCHEMBL10762081 | 0.72 | ALDH1A1 (0.59) | ALDH1A1TSHRKMT2AHTT | |
| Ethylenediamine SCHEMBL1472377 | 0.69 | ALDH1A1 (0.52) | ALDH1A1TSHRKMT2AHTT | |
| SCHEMBL27473190 | 0.69 | ALDH1A1 (0.52) | ALDH1A1TSHRKMT2AHTT | |
| SCHEMBL7834284 | 0.68 | KMT2A (0.52) | ALDH1A1TSHRKMT2AMEN1AGTR1 | |
| SCHEMBL7834292 | 0.68 | KMT2A (0.52) | ALDH1A1TSHRKMT2AMEN1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500864-B1 | ANTIMUSCARINIC BRONCHODILATORS | PFIZER LTD (GB) | 2001-09-19 | — | — | EP | disclosed |
| US-5292749-A | Quinuclidine derivatives; bronchodilator agents, treatment of respiratory system disorders | PFIZER INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0500864-A1 | ANTIMUSCARINIC BRONCHODILATORS | Pfizer Limited (GB) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004346-A1 | ANTIMUSCARINIC BRONCHODILATORS | PFIZER LIMITED (GB) | 1992-03-19 | — | — | WO | disclosed |