Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | ASPH | Q12797 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29715790 | 0.98 | NOTUM (0.41) | NOTUMASPHHPGDKDM4EKDM4C | |
| SCHEMBL28158873 | 0.82 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL12956800 | 0.82 | ALDH1A1 (0.33) | NOTUMKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL1832559 | 0.82 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL727645 | 0.82 | PARP1 (0.37) | KDM4EALDH1A1KMT2AMAP2K4 | |
| Niacin SCHEMBL28265838 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL1406288 | 0.80 | ALDH1A1 (0.33) | NOTUMKDM4CALDH1A1KMT2ACYP1A2 | |
| SCHEMBL13373959 | 0.80 | NOTUM (0.38) | NOTUMKDM4EKDM4CALDH1A1KMT2A | |
| SCHEMBL3906252 | 0.79 | CFTR (0.43) | NOTUMKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL12450297 | 0.79 | KDM4E (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775207-A | Morpholine-containing amide compound and preparation method and application thereof | 山东农业大学 | 2025-04-08 | — | — | CN | claimed |
| CN-118616022-B | Application of metal organic framework material in liquid phase separation of hexane isomers | 同济大学 | 2024-11-12 | — | — | CN | claimed |
| CN-118616022-A | Application of metal organic framework material in liquid phase separation of hexane isomers | 同济大学 | 2024-09-10 | — | — | CN | claimed |
| CN-114957124-B | 3- (trifluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2023-11-07 | — | — | CN | claimed |
| CN-114957124-A | 3- (trifluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2022-08-30 | — | — | CN | claimed |
| CN-107929271-A | For the sGC stimulants or sGC activator treated the independent of cystic fibrosis and combined with PDE5 inhibitor | 阿德弗里奥药品有限责任公司 | 2018-04-20 | — | — | CN | claimed |
| CN-106279024-A | A kind of xanthine oxidoreductase inhibitors and preparation method and application | 华南理工大学 | 2017-01-04 | — | — | CN | claimed |
| US-6911453-B2 | Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-06-28 | — | — | US | claimed |
| US-20040044211-A1 | Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | US | claimed |
| EP-4066898-B1 | BENZIMIDAZOLE COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDAL AND ACARICIDAL AGENT COMPRISING SAID COMPOUND, AND METHOD FOR USING SAID INSECTICIDAL AND ACARICIDAL AGENT | NIHON NOHYAKU CO LTD (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-10-09 | — | — | US | disclosed |
| US-12389911-B2 | Benzimidazole compound or salt thereof, agricultural and horticultural insecticidal and acaricidal agent containing said compound, and method for using same | NIHON NOHYAKU CO., LTD. (JP) | 2025-08-19 | — | — | US | disclosed |
| EP-4536653-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | Eisai R&D Management Co., Ltd. (JP) | 2025-04-16 | — | — | EP | disclosed |
| CN-119775207-A | Morpholine-containing amide compound and preparation method and application thereof | 山东农业大学 | 2025-04-08 | — | — | CN | disclosed |
| US-6706911-B1 | REACTING N-SUBSTITUTED 3-AMINOACRYLIC ESTERS WITH HALOALKYLCARBOXYLIC ANHYDRIDES IN PRESENCE OF BASE; PYRAZOLE-4-CARBOXYLIC ACID CHEMICAL INTERMEDIATES; HALOACYLATION | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | disclosed |
| US-20040044211-A1 | Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | US | disclosed |
| WO-2003068743-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-21 | — | — | WO | disclosed |
| CN-1045439-C | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1999-10-06 | — | — | CN | disclosed |
| CN-1104636-A | New compositions of matter | RHONE POULENC AGRICULTURE (FR) | 1995-07-05 | — | — | CN | disclosed |
| CN-1085219-A | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1994-04-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | NEU1, NEU2, NEU4 | NOTUM 980/4885ASPH 555/4885HPGD 1182/4885 |
| US-12389911-B2 | Benzimidazole compound or salt thereof, agricultural and horticultural insecticidal and acaricidal agent containing said compound, and method for using same | HDAC6, HDAC2, HDAC1 | NOTUM 53/4885ASPH 719/4885HPGD 4069/4885 |
| US-20040044211-A1 | Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them | ABCB11, SLC10A1, PON1 | NOTUM 2703/4885ASPH 674/4885HPGD 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.