Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783526 | 0.82 | NOTUM (0.38) | KMT2AKDM4EALDH1A1MAP2K4 | |
| Hydrochloric Acid SCHEMBL29715790 | 0.81 | NOTUM (0.41) | KMT2AKDM4EALDH1A1MAP2K4 | |
| SCHEMBL12956800 | 0.81 | ALDH1A1 (0.33) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL1832559 | 0.81 | MAPK1 (0.39) | — | |
| SCHEMBL28158873 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL5647128 | 0.79 | KDM4E (0.31) | KDM4E | |
| SCHEMBL3906252 | 0.78 | CFTR (0.43) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL12450297 | 0.78 | KDM4E (0.31) | KDM4E | |
| Hydrochloric Acid SCHEMBL4664362 | 0.77 | KDM4E (0.30) | KDM4E | |
| SCHEMBL28749860 | 0.77 | KDM4E (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311847-A | PYRAZOLE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | 卡尔维斯塔制药有限公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109195965-A | The inhibitor that WDR5 protein-protein combines | 普罗佩纶治疗公司 | 2019-01-11 | — | — | CN | claimed |
| CN-105601618-B | Aromatic imides class compound and preparation method and application | 天津医科大学 | 2018-04-27 | — | — | CN | claimed |
| EP-3030568-A1 | THIENO[2,3-C]PYRANS AS CFTR MODULATORS | Galapagos NV (BE) | 2016-06-15 | — | — | EP | claimed |
| EP-2879494-A1 | COMPOSITION COMPRISING A PESTICIDAL TERPENE MIXTURE AND A FUNGICIDE | Bayer CropScience AG (DE) | 2015-06-10 | — | — | EP | claimed |
| WO-2015018823-A1 | THIENO[2,3-C]PYRANS AS CFTR MODULATORS | GALAPAGOS NV (BE) | 2015-02-12 | — | — | WO | claimed |
| WO-2014020109-A1 | COMPOSITION COMPRISING A PESTICIDAL TERPENE MIXTURE AND A FUNGICIDE | BAYER CROPSCIENCE AG (DE) | 2014-02-06 | — | — | WO | claimed |
| JP-2011527306-A | — | — | 2011-10-27 | — | — | JP | claimed |
| EP-2317856-A1 | PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS II | BASF SE (DE) | 2011-05-11 | — | — | EP | claimed |
| EP-2219456-A1 | PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS | BASF SE (DE) | 2010-08-25 | — | — | EP | claimed |
| WO-2009062905-A1 | PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS | BASF SE (DE) | 2009-05-22 | — | — | WO | claimed |
| US-20250074903-A1 | N-((HET)Arylmethyl)-Heteroaryl-Carboxamides Compounds As Kallikrein Inhibitors | DRI UK LP (KY) | 2025-03-06 | — | — | US | disclosed |
| CN-115715290-A | 2- (hetero) aryl-substituted fused heterocyclic derivatives as pesticides | 拜耳公司 | 2023-02-24 | — | — | CN | disclosed |
| US-20230014907-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED | 2023-01-19 | — | — | US | disclosed |
| WO-2022261433-A1 | EXTENDER COMPOSITIONS AND USE THEREOF TO INCREASE ON-SEED ADHERENCE AND STABILITY OF MICROBES | PIVOT BIO, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| US-20090042724-A1 | Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-12 | — | — | US | disclosed |
| CN-100381049-C | Aqueous suspension preparation of bactericide for folieage application | MITSUI CHEMICALS INC (JP) | 2008-04-16 | — | — | CN | disclosed |
| CN-1826052-A | Aqueous suspension of bactericide for stem and leaf spreading | MITSUI CHEMICALS INC (JP) | 2006-08-30 | — | — | CN | disclosed |
| US-20050107428-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2005-05-19 | — | — | US | disclosed |
| CN-1078234-A | Pyrazole carboxanilide fungicide | MONSANTO CO (US) | 1993-11-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107428-A1 | Chemical compounds | CCR10, CCR3, CXCR5 | PARP1 3394/4885CCNC 432/4885CDK8 2728/4885 |
| US-20230014907-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | APOL1, APOB, NPC1L1 | PARP1 4396/4885CCNC 4493/4885CDK8 4124/4885 |
| US-20090042724-A1 | Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides | CBR3, CBR1, SNU13 | PARP1 4085/4885CCNC 574/4885CDK8 2065/4885 |
| US-20250074903-A1 | N-((HET)Arylmethyl)-Heteroaryl-Carboxamides Compounds As Kallikrein Inhibitors | KLKB1, BDKRB1, BDKRB2 | PARP1 1516/4885CCNC 3112/4885CDK8 1338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.