Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328885 | 0.85 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7823722 | 0.83 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8413634 | 0.81 | RAB9A (0.55) | RAB9ANPC1CASP1MEN1KMT2A | |
| SCHEMBL8413632 | 0.81 | RAB9A (0.55) | RAB9ANPC1CASP1MEN1KMT2A | |
| SCHEMBL23934179 | 0.80 | RAB9A (0.47) | RAB9ANPC1CASP1MEN1KMT2A | |
| SCHEMBL9198473 | 0.80 | MEN1 (0.70) | RAB9ANPC1CASP1MEN1KMT2A | |
| SCHEMBL2839586 | 0.76 | MEN1 (0.68) | RAB9ANPC1CASP1MEN1KMT2A | |
| SCHEMBL27718015 | 0.75 | NPC1 (0.56) | RAB9ANPC1CASP1MEN1KMT2A | |
| SCHEMBL21998667 | 0.74 | MEN1 (0.66) | RAB9ANPC1CASP1MEN1KMT2A | |
| SCHEMBL21998749 | 0.74 | MEN1 (0.66) | RAB9ANPC1CASP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498723-B1 | Nitrogen containing bicycle compounds, method for their preparation, their use as pharmaceutical and compositions containing them | AVENTIS PHARMA SA (FR) | 2001-09-19 | — | — | EP | disclosed |
| EP-0498721-B1 | N-substituted quinoline derivatives, process for their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1999-12-22 | — | — | EP | disclosed |
| EP-0498723-A1 | Nitrogen containing bicycle compounds, method for their preparation, their use as pharmaceutical and compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |
| EP-0498721-A1 | N-substituted quinoline derivatives, process for their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |