Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413634 | 1.00 | RAB9A (0.55) | RAB9ANPC1CASP1GAAKMT2A | |
| SCHEMBL8410515 | 0.86 | RAB9A (0.55) | RAB9ANPC1KMT2ALMNAHPGD | |
| SCHEMBL8410518 | 0.86 | RAB9A (0.55) | RAB9ANPC1KMT2ALMNAHPGD | |
| SCHEMBL8410078 | 0.84 | ALDH1A1 (0.47) | RAB9ANPC1GAAKMT2AMEN1 | |
| SCHEMBL8410081 | 0.84 | ALDH1A1 (0.47) | RAB9ANPC1GAAKMT2AMEN1 | |
| SCHEMBL7835265 | 0.81 | RAB9A (0.56) | RAB9ANPC1CASP1GAAKMT2A | |
| SCHEMBL9198473 | 0.77 | MEN1 (0.70) | RAB9ANPC1CASP1GAAKMT2A | |
| SCHEMBL8501792 | 0.74 | MEN1 (0.51) | RAB9ANPC1GAAKMT2AMEN1 | |
| SCHEMBL8410470 | 0.74 | MEN1 (0.51) | RAB9ANPC1GAAKMT2AMEN1 | |
| SCHEMBL5636399 | 0.73 | RAB9A (0.72) | RAB9ANPC1CASP1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985894-A | USEFUL IN THE TREATMENT OF CARDIOVASCULAR ILLNESSES | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |