Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MDH1 | P40925 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835265 | 0.85 | RAB9A (0.56) | RAB9AALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL8410515 | 0.82 | RAB9A (0.55) | RAB9AALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8410518 | 0.82 | RAB9A (0.55) | RAB9AALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL7575475 | 0.82 | ALDH1A1 (0.70) | RAB9AALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL7823722 | 0.81 | MEN1 (0.55) | ALDH1A1HPGDCYP2C19SMN1; SMN2MAPT | |
| SCHEMBL7836111 | 0.79 | MEN1 (0.56) | RAB9AALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL21998681 | 0.77 | ALDH1A1 (0.67) | RAB9AALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL21998673 | 0.77 | ALDH1A1 (0.67) | RAB9AALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL21998663 | 0.77 | ALDH1A1 (0.67) | RAB9AALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL25933608 | 0.73 | HTR7 (0.58) | RAB9AALDH1A1HPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498721-B1 | N-substituted quinoline derivatives, process for their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1999-12-22 | — | — | EP | disclosed |
| EP-0498721-A1 | N-substituted quinoline derivatives, process for their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |