Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831681 | 0.93 | NPC1 (0.47) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7834035 | 0.92 | ALDH1A1 (0.44) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7821036 | 0.91 | MAPT (0.40) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7835953 | 0.89 | ALDH1A1 (0.43) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7821006 | 0.86 | ALDH1A1 (0.45) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7813272 | 0.85 | ALDH1A1 (0.44) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7821104 | 0.85 | NPC1 (0.44) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9563431 | 0.84 | SMN1; SMN2 (0.46) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7830610 | 0.84 | SLC10A2 (0.47) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7812297 | 0.84 | KMT2A (0.42) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |