Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | EDNRB | P24530 | 11/20 | 0.44 |
| ▸ | EDNRA | P25101 | 5/20 | 0.44 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835143 | 0.91 | ALDH1A1 (0.42) | ALDH1A1MAPTRAB9AL3MBTL1EDNRB | |
| SCHEMBL7834035 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL7835405 | 0.86 | NPC1 (0.41) | ALDH1A1MAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL7831681 | 0.86 | NPC1 (0.47) | ALDH1A1MAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL7835953 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL7813272 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL9563431 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1MAPTRAB9AL3MBTL1PDE1A | |
| SCHEMBL7812297 | 0.81 | KMT2A (0.42) | ALDH1A1MAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL7830610 | 0.79 | SLC10A2 (0.47) | ALDH1A1MAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL7809634 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTRAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |