Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | CYBB | P04839 | 1/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846207 | 0.87 | TLR7 (0.42) | KMT2AMEN1CYP3A4 | |
| SCHEMBL7848800 | 0.86 | KDM4E (0.34) | GRIN1GRIN2BKMT2AMEN1 | |
| SCHEMBL7847304 | 0.84 | GRIN1 (0.44) | GRIN1GRIN2BGABRA1GABRA5PKM | |
| SCHEMBL6086769 | 0.84 | GRIN1 (0.43) | GRIN1GRIN2BGABRA1GABRA5PKM | |
| SCHEMBL7837526 | 0.82 | MTNR1A (0.52) | GRIN1GRIN2BKMT2AMEN1CYP1A2 | |
| SCHEMBL7847101 | 0.82 | GRIN1 (0.45) | GRIN1GRIN2BGABRA1GABRA5KDM5B | |
| SCHEMBL7843323 | 0.81 | GRIN1 (0.36) | GRIN1GRIN2BKMT2A | |
| SCHEMBL7848233 | 0.81 | MTNR1A (0.39) | GRIN1GRIN2BKMT2AMEN1 | |
| SCHEMBL7844132 | 0.81 | ALDH1A1 (0.37) | KMT2AMEN1 | |
| SCHEMBL7848304 | 0.79 | TLR7 (0.33) | GRIN1GRIN2BKDM5BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |