Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848800 | 0.92 | KDM4E (0.34) | GRIN1GRIN2BKMT2AKDM4EP2RX3 | |
| SCHEMBL7848233 | 0.87 | MTNR1A (0.39) | GRIN1GRIN2BKMT2AROCK2KDM4E | |
| SCHEMBL7846207 | 0.86 | TLR7 (0.42) | KMT2AKDM4EP2RX3TLR7ALDH1A1 | |
| SCHEMBL7844403 | 0.83 | GRIN1 (0.37) | GRIN1GRIN2BKMT2AROCK2KDM4E | |
| SCHEMBL6088310 | 0.82 | GRIN1 (0.36) | GRIN1GRIN2BKMT2AROCK2TLR7 | |
| SCHEMBL7837526 | 0.82 | MTNR1A (0.52) | GRIN1GRIN2BKMT2AKDM4EMTNR1A | |
| SCHEMBL7835808 | 0.81 | GRIN1 (0.43) | GRIN1GRIN2BKMT2A | |
| SCHEMBL7844132 | 0.80 | ALDH1A1 (0.37) | KMT2AKDM4EP2RX3TLR7MTNR1A | |
| SCHEMBL7847745 | 0.78 | ELANE (0.32) | GRIN1GRIN2BKMT2AALDH1A1 | |
| SCHEMBL7849648 | 0.78 | GRIN1 (0.36) | GRIN1GRIN2BCASRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |