Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848800 | 0.92 | KDM4E (0.34) | MTNR1AMTNR1BKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7837526 | 0.90 | MTNR1A (0.52) | MTNR1AMTNR1BKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7843323 | 0.87 | GRIN1 (0.36) | MTNR1AMTNR1BKDM4EALDH1A1KMT2A | |
| SCHEMBL7846207 | 0.86 | TLR7 (0.42) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7837064 | 0.83 | HSD17B10 (0.39) | MTNR1AMTNR1BKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6088314 | 0.82 | MTNR1A (0.37) | MTNR1AMTNR1BKDM4EALDH1A1MEN1 | |
| SCHEMBL7835808 | 0.81 | GRIN1 (0.43) | MEN1KMT2AGRIN1GRIN2B | |
| SCHEMBL7845270 | 0.81 | MTNR1A (0.38) | MTNR1AMTNR1BKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7844132 | 0.80 | ALDH1A1 (0.37) | MTNR1AMTNR1BKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7848710 | 0.80 | MTNR1A (0.37) | MTNR1AMTNR1BKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |