Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.42 |
| ▸ | NCF1 | P14598 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841786 | 0.96 | RARB (0.47) | RARBNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7842632 | 0.90 | NR5A1 (0.53) | RARBNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7837947 | 0.90 | NR5A1 (0.53) | RARBNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7838004 | 0.85 | NPC1 (0.51) | RARBNPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7838812 | 0.85 | NPC1 (0.51) | RARBNPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7883583 | 0.84 | NPC1 (0.63) | RARBNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7838682 | 0.83 | ALOX5 (0.47) | RARBNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7838536 | 0.81 | ALOX5 (0.44) | RARBNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7883585 | 0.81 | NPC1 (0.55) | RARBNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8748273 | 0.80 | NPC1 (0.57) | RARBNPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751133-B1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI CHEMICALS INC (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5770108-A | HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0751133-A1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-01-02 | — | — | EP | disclosed |