Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838682 | 0.97 | ALOX5 (0.47) | ALOX5RARBKDM4EMAPK1TDP1 | |
| SCHEMBL7841558 | 0.95 | ALOX5 (0.49) | ALOX5RARBKDM4EGPBAR1CYSLTR2 | |
| SCHEMBL7841191 | 0.95 | ALOX5 (0.49) | ALOX5RARBKDM4EGPBAR1CYSLTR2 | |
| SCHEMBL7830297 | 0.89 | RARB (0.47) | RARBRARANPC1SMN1; SMN2PLA2G4B | |
| SCHEMBL7828167 | 0.89 | RARB (0.47) | RARBRARANPC1SMN1; SMN2PLA2G4B | |
| SCHEMBL7841786 | 0.85 | RARB (0.47) | RARBKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7737535 | 0.84 | NPC1 (0.56) | RARBKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8396421 | 0.83 | GPBAR1 (0.47) | GPBAR1CYSLTR2CYSLTR1 | |
| SCHEMBL8748478 | 0.82 | RAB9A (0.50) | RARBKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8748498 | 0.82 | RAB9A (0.50) | RARBKDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751133-B1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI CHEMICALS INC (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5770108-A | HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0751133-A1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-01-02 | — | — | EP | disclosed |