SCHEMBL7842632

SCHEMBL7842632

CCCCCCCCCCOc1ccc2cc(-c3ncc(O)cn3)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.53
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50
KDM4E B2RXH2 1/20 0.50
THRA P10827 1/20 0.48
MAPT P10636 1/20 0.48
RARB P10826 3/20 0.48
LTA4H P09960 1/20 0.47
SPHK2 Q9NRA0 3/20 0.46
PTPN11 Q06124 1/20 0.46
SPHK1 Q9NYA1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7837947 1.00 NR5A1 (0.53) NR5A1NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL7841786 0.94 RARB (0.47) NR5A1NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL7835844 0.90 RARB (0.50) NPC1RAB9ASMN1; SMN2HSD17B10KDM4E
SCHEMBL9513828 0.87 NPC1 (0.65) NR5A1NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL6534975 0.87 NPC1 (0.65) NR5A1NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL7506953 0.87 NPC1 (0.65) NR5A1NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL7877116 0.87 NPC1 (0.65) NR5A1NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL7849805 0.86 NR5A1 (0.53) NR5A1NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL7839694 0.86 NR5A1 (0.53) NR5A1NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL7841530 0.86 NR5A1 (0.56) NR5A1NPC1RAB9ASMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751133-B1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI CHEMICALS INC (JP) 2001-09-12 EP disclosed
US-5770108-A HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0751133-A1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-02 EP disclosed