Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376781 | 0.76 | ALDH1A1 (0.45) | RAB9APOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16191048 | 0.67 | HTR2A (0.51) | RAB9APOLBHTR2AHTR2CALDH1A1 | |
| SCHEMBL12040567 | 0.67 | HTR2A (0.55) | RAB9APOLBHTR2AHTR2CMEN1 | |
| SCHEMBL3466033 | 0.66 | HIF1A (0.50) | HTR2AALDH1A1SMN1; SMN2LMNATAAR1 | |
| SCHEMBL654154 | 0.66 | TAAR1 (0.56) | RAB9AALDH1A1LMNATAAR1PLAAT3 | |
| SCHEMBL7835892 | 0.66 | RAB9A (0.57) | RAB9APOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8591746 | 0.65 | TAAR1 (0.65) | ALDH1A1LMNATAAR1 | |
| SCHEMBL3362041 | 0.64 | ALOX5 (0.50) | RAB9APOLBHTR2AHTR2CSMN1; SMN2 | |
| SCHEMBL9340736 | 0.64 | CA12 (0.62) | RAB9APOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9340734 | 0.64 | CA12 (0.62) | RAB9APOLBALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582789-B1 | Novel 7-(substituted)-8-(substituted)-9-(substituted glycyl)amido-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 2001-10-04 | — | — | EP | claimed |
| EP-0582789-B1 | Novel 7-(substituted)-8-(substituted)-9-(substituted glycyl)amido-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 2001-10-04 | — | — | EP | disclosed |