Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALPG | P10696 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8836716 | 1.00 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL8836081 | 0.82 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL783597 | 0.77 | KMT2A (0.63) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL4361229 | 0.75 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL19668743 | 0.75 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL6176444 | 0.75 | LTA4H (0.50) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL7199609 | 0.74 | LMNA (0.60) | ALDH1A1SMN1; SMN2KMT2ARAB9AHPGD | |
| SCHEMBL8836116 | 0.73 | POLB (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL27380660 | 0.73 | POLB (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL8836398 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2KMT2ATACR3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075965-A | New Hete rocyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-09-08 | — | — | CN | disclosed |
| CN-1070404-A | New Hete rocyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-03-31 | — | — | CN | disclosed |