Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 6/20 | 0.49 |
| ▸ | CMA1 | P23946 | 5/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837711 | 0.81 | CTSG (0.57) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7837210 | 0.79 | CTSG (0.60) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7836334 | 0.78 | NPC1 (0.49) | CTSLCTSSCTSKCTSBCTSG | |
| SCHEMBL7835603 | 0.77 | CTSG (0.63) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7825623 | 0.76 | CTSG (0.61) | CTSGCMA1PRSS1CTRB1NPC1 | |
| SCHEMBL7826784 | 0.76 | CTSG (0.64) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7837132 | 0.75 | CTSG (0.82) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7835767 | 0.74 | PRSS1 (0.56) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7837407 | 0.72 | PRSS1 (0.54) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL5529603 | 0.70 | CTSL (0.80) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORP (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5866592-A | Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same | NIPPON STEEL CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |