Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 12/20 | 0.64 |
| ▸ | CMA1 | P23946 | 11/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.59 |
| ▸ | CTRB1 | P17538 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835603 | 0.96 | CTSG (0.63) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7837210 | 0.91 | CTSG (0.60) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7837711 | 0.86 | CTSG (0.57) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7837132 | 0.82 | CTSG (0.82) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7835767 | 0.77 | PRSS1 (0.56) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7826783 | 0.76 | CTSG (0.47) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7836337 | 0.76 | CTSL (0.50) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7837407 | 0.75 | PRSS1 (0.54) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL27517270 | 0.73 | MEN1 (0.55) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7825862 | 0.73 | CTSG (0.80) | CTSGCMA1PRSS1CTRB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORP (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5866592-A | Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same | NIPPON STEEL CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |