Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.54 |
| ▸ | CTSK | P43235 | 5/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10188447 | 0.87 | ATM (0.56) | CTSSCTSKSYKATMCTSL | |
| SCHEMBL14974845 | 0.86 | LDHA (0.48) | SYKATM | |
| SCHEMBL22153160 | 0.84 | CTSS (0.53) | CTSSCTSKSYKOPRM1 | |
| SCHEMBL29333309 | 0.83 | ATM (0.60) | CTSSCTSKSYKATMOPRM1 | |
| SCHEMBL20425275 | 0.82 | SYK (0.53) | SYKATMADRB2ADRB1ADRB3 | |
| SCHEMBL20805990 | 0.82 | CTSS (0.51) | CTSSCTSKSYKATMMIF | |
| SCHEMBL13633798 | 0.81 | CTSS (0.50) | CTSSCTSKSYKATMMIF | |
| SCHEMBL17592938 | 0.80 | CTSS (0.49) | CTSSCTSKSYKESR1ESR2 | |
| SCHEMBL3900446 | 0.80 | PPARG (0.46) | CTSSCTSKSYKATMCTSL | |
| SCHEMBL1553366 | 0.79 | SMN1; SMN2 (0.51) | CTSSCTSKSYKMIFADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140849-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040560-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |