Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | UGT2B17 | O75795 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184305 | 0.78 | ALDH1A1 (0.32) | TYMSBRD4ALDH1A1L3MBTL1HTT | |
| SCHEMBL29237681 | 0.77 | SMN1; SMN2 (0.33) | TYMSALDH1A1L3MBTL1CA1CA2 | |
| SCHEMBL12261408 | 0.73 | ALDH1A1 (0.50) | TYMSALDH1A1L3MBTL1CA1CA2 | |
| SCHEMBL29237816 | 0.73 | ALDH1A1 (0.33) | TYMSALDH1A1KMT2ATSHR | |
| SCHEMBL9056337 | 0.69 | PGR (0.44) | BRD4ALDH1A1HTTKMT2ATSHR | |
| SCHEMBL2351057 | 0.69 | METAP1 (0.49) | BRD4ALDH1A1HTTCA1CA2 | |
| SCHEMBL14361126 | 0.69 | TSHR (0.36) | ALDH1A1KMT2ATSHR | |
| SCHEMBL16527051 | 0.68 | SMN1; SMN2 (0.43) | TYMSBRD4ALDH1A1KMT2ATSHR | |
| SCHEMBL14430333 | 0.68 | TGM2 (0.42) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL30173214 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843666-B1 | 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-05-16 | — | — | EP | disclosed |
| CN-1188473-A | 4-substituted 5-polycyclylpyrimidine herbicides | DOWELANCO (US) | 1998-07-22 | — | — | CN | disclosed |
| US-5780465-A | 4-substituted 5-polycyclylpyrimidine herbicides | DOW AGROSCIENCES LLC (US) | 1998-07-14 | — | — | US | disclosed |